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4-Aminosalicylic Acid 유도체의 합성연구(II) 2-Ethoxy-4-acetamidobenzamide의 합성

Studies on 4-Aminosalicylic Acid Derivatives (II). Synthesis of 2-Ethoxy-4-acetamidobenzamide

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2-Ethoxy-4-acetamidobenzoate(III) was synthesized by ethylation of N-formyl compound obtained with formulation of methyl 4-aminosalicylate and 2-ethoxy-4-acetamidobenzamide (VIII) was synthesized by ethylation of 4-acetamidosalicylamide (VII) formed by reacting methyl 4-acetamido-2-acetoxy benzoate with concentrated ammonia water under pressure. 2-Ethoxy-4-acetamido benzamide (VIII) was also synthesized by acetylation of 2-ethoxy-4-aminobenzamide (VI) obtained by pressure reaction of methyl 2-ethoxy-4-formylamidobenzoate (I) with concentrated ammonia water.

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