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대극과식물 등대풀로부터 분리한 가수분해형 탄닌의 tyrosinase활성억제효과

Inhibitory Effect of Hydrolysable Tannins Isolated from the Euphorbia helioscopia on Mushroom Yrosinase Activitiy in vitro

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Nineteen hydrolyable tannins isolated from Euphorbia helioscopia(Euphorbiaceae) were tested for the inhibitory effect on mushroom tyrosinase activity in vitro. Inhibitory effect of gallotannin group exhibited more potent than that of phenocarboxylic acid and ellagitannin groups against the enzyme activity. The inhibitory activity by pentagalloyl glucose on mushroom tyrosinase was more potent(IC50, 4.9uM) than that of kojic acid(IC50, 8.7uM)

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