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백출의 에탄을 추출물에 의한 Melanin생성억제 효과

Inhibitory Effects of Ethanol Extract of Atractylodis Rhizoma alba on Melanin Biosynthesis

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The inhibitory effect of extract of Atractylodis Rhizoma alba on melanin biogenesis was studied by using B16/F10 melanoma in culture. Atractylodis Rhizoma alba significantly inhibited tryrsinase activity, and melanin contents with or without alpha-MSH and forskolin in vitro. Melanin contents and tryosinase aotivity have decreased in a dose-dependent manner, These results show that extract of Atractyledis Rhifoma alba could be developed as skin whitening components of cosmetics.

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