학술저널
진세노사이드 Rh2의 방향선택적 합성
Regioselective Synthesis of Ginsenoside Rh2
- 대한약학회
- 약학회지
- 제45권 제4호 (2001년)
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2001.08328 - 333 (6 pages)
- 14
Ginsenoside Rh2, a minor glycoside constituent of the red ginseng is known as an unique antitumor compound. Several attempts to prepare it in a large scale including semisynthesis from bettalafolientriol, an 3-epimer of 20(S)-protopanaxadiol, has been reported. We have previously reported a synthesis of ginsenoside Rh2 from 20(S)-protopanaxadiol obtained by alkaline hydrolysis of total ginsenoside. The regioselective synthesis of this compound was achieved by protection of 12-OH group.
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