학술저널
HPLC를 이용한 제에웅의 레티놀 유도체 정량
Determination of Retinols in Pharmaceutical Preparations by HPLC
- 대한약학회
- 약학회지
- 제45권 제4호 (2001년)
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2001.08357 - 365 (9 pages)
- 46
A simple and rapid determination of total retinol from various pharmaceuticals containing retinol derivatives was described. Retinol derivatives were hydrolyzed with alcoholic KOH to alcoholic retinol, which was determined by HPLC. Pretreatments and HPLC conditions depend on the kind of retinols and preparation forms. The total amount of alcoholic retinol could be determined with this method from many pharmaceutical preparation of retinol derivatives. Treating time of KOH, acidic reagents and HPLC conditions were investigated.
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