한국인 장기조직중 유기염소제류 농약의 분포

Distribution of Organochlorine Pesticides in Korean Human Tissues

Persistent organochlorine pesticides has been used intensively in agriculture for a long time. The occurrence of organochlorine pesticides in the environment and subsequently in parts of the food chains, results in the intake of these compounds by human and animal. The measurement of the levels of organochlorine pesticides in tissues or blood of human populations is a good marker in evaluating the extent of exposure and hazards. So, most countries have conducted initial monitoring programs to determine organochlorine pesticides and polychlorinated biphenyls in human tissues. But, in Korea, a few research has been reported. In this study the legally prohibited organochlorines, such as, α-BHC, β-BHC, γ-BHC, δ-BHC, p,p'-DDT p,p'-DDD, p,p'-ODE, endrin, dieldrin and aldrin were determined in human blood, brain, adipose tissue, kidney cortex and liver tissues collected at autopsy of 10 men and 10 women, 16-65 years of age. Almost all the organochlorine pesticides mentioned previously were determined in human tissue samples indicated that they have been widely distributed in Korean human body: No significant difference was found in the levels of organochlorine pesticides between sexes, districts and ages.