Infrared Spectrophotometry에 의한 의약품의 분석연구(II) 적외선흡수 Spectra에 의한 Sulamithoxydiazine 및 Sulfamethosypyridazine의 정량분석

Analysis of Drugs and Chemicals by Infrared Absorption Spectrophotemetry(II) Quantitative Analysis of Sulfamethosydiazine and Sulfamethosypyridazine in Pharmaceutical Preparations

In quantitative analysis of sulfonamide drugs by means of infrared Spectrophotometry, the author tried to analyse Sulfamethoxydiazine and Sulfa methoxypyridazine in their Pharmaceutical Preparations. By the survey of infrared absorption spectra of Sulfamethoxydiazine and Sulfamethoxypyridazine, We found quantitative properties at the peaks of wave number 1150 cm-1 (Sulfamethoxydiazine) and 1090 cm-1 (Sulfamethoxypyridazine) in the spectra. These peaks obey Beer''s Law in a range of 50-150mcg for Sulfamethoxydiazine and 70-350pg for Sulfamethoxypyridazine in 300mg KBr disc. By this method, Sulfamethoxydiazine and Sulfamethoxypyridazine could be analyzed less than 2% error.