학술저널
개다래의 고요산혈증 개선 활성
Hypouricemic Activity of Actinidia polygama
- 대한약학회
- 약학회지
- 제47권 제5호 (2003년)
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2003.10307 - 310 (4 pages)
- 100
Ethanol extract of Actinidia polygama Max. (AP) was examined for hypouricemic activity in potassium oxonate-induced hyperuricemic animal model. Ethanol extract of AP lowered the plasma uric acid level by 20% when compared to the hyperuricemic control group. AP ether fraction at a dose of 100 mg/kg showed 27% reduction, whose efficacy was comparable to the probenecid-treated group. AP ether fraction-treated group also showed 23% reduction of urate in urine and this result suggests that AP ether fraction has anti-gout activity probably due to xanthine oxidase inhibition.
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