학술저널
임상분리 호흡기 감염증 원인 균주에서의 Macrolide계 항생물질의 내성
The Prevalence of Macrolide Antibiotics Resistance in the Clinical Isolates of Common Respiratory Pathogens
- 대한약학회
- 약학회지
- 제48권 제6호 (2004년)
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2004.12364 - 368 (5 pages)
- 3
The prevalence of resistance to a range of macrolides was determined for clinical isolates of common respiratory pathogens using NCCLS testing methods and interpretative criteria.71.4% of Streptococcus pneumoniae, 62.3% of Staphylococcus aureus, 50.8% of coagulase-negative staphylococci and 4.4% of Strpetococcus pyogenes were erythromycin resistant. Also, the rates of resistance to other macrolides and clindamycin in these clinical isolates were as high as to eryth -romycin. Almost all of the macrolide-resistant isolates were positive for erm of the methylase gene, or mef of the efflux gene.
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