학술저널
3-메톡시-6-알릴치오피리다진의 사람 췌장암 세포 사멸작용
Induction of Apoptosis by 3-Methoxy-6-Allylthiopyridazine in Human Pancreatic Cancer Cell
- 대한약학회
- 약학회지
- 제49권 제4호 (2005년)
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2005.08335 - 339 (5 pages)
- 4
In this study we investigated the effect of 3-methoxy-6-allylthiopyridazine on cell growth in BxPC3 and PANC1 human pancreatic cancer cells. The treatment with 3-methoxy-6-allylthiopyridazine for 48 h decreased cell viability and induced apoptotic cell death in a dose-dependent manner, assessed by using the MTT assay and the flow cytometry, respectively. These results suggest that 3-methoxy-6-allylthiopyridazine may be a good candidate for the therapeutic management of human pancreatic cancers.
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