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안개 D형 저지원을 갖는 MLS 내성 황색 포도상 구균의 분포와 내성 기전

Characterization of S. aureus Showing MLS Resistance with Foggy D Shape (fMLS)

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A new type of macrolides, lincosamides and streptogramin B antibiotics (MLS) resistance, showing the characteristic phenotype growing within the inhibition zone area around the clindamycin disk, was identified among clinically isolated Staphylococcus aureus. We named the phenotype as MLS resistance with foggy-D shape (fMLS). The average frequency of fMLS isolates was 9%. All of fMLS isolates have only erm(A) for the resistance determinant. The growth pat- tern of the challenged fMLS isolate looks intermediate phase between the patterns of inducible MLS resistance and constitutive MLS resistance.

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