Methyl Orange에 의한 4급 Amine류의 Ion Pair 유출 흡광도 정량(I) Cetyltrimethylammonium bromide, Bretylium tosylate, Gallamine triethiodide 및 Thiamine의 정량

Spectrophotometric Determination of Ion Pair Extraction of Quaternary Amines with Methyl Orange

Methyl orange(MO) and cetyltrimethylammonium bromide(CTA) were mixed and added to 10ml of the buffer solution and then the solution was shaken for 5 minutes. The maximum absorption wavelength of the reaction product was 419nm. Dichloromethane was the best extracting solvent among the several organic solvents and the most suitable pH range was 2-8. When the CTA-MO calibration curve was made in the best experimental condition, the Lambert-Beer''s law was obeyed in the range of CTA concentration of 1.5 X 10-5-1.0 X 10-4M by UV spectrophotometer. This method was possible to determine quaternary ammonium salts in the pharmaceutical preparations.