학술저널
Bacillus licheniformis EMR-1에서의 MLS 유도내성 기전 erm K의 크로닝
MLS Inducible Resistance Mechanism in Bacillus licheniformis EMR-1 Cloning of erm K, a MLS Resistance Determinant
- 대한약학회
- 약학회지
- 제32권 제4호 (1988년)
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1988.08213 - 221 (9 pages)
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Inducible MLS resistance gene of Bacillus licheniformis specified by erm K was subcloned in Bacillus subtilis, and the DNA sequence corresponding to its control region was determined. The determinant erm K was in Pvu II=Hind III fragment, which was 1.3 kb. The leader region is capable of forming a complex series of inverted complementary repeat sequences(ICRS) centering on at least six axes of symmetry, some of them mutually exclusive, in a way that resulted ultimately in post-transcriptional unmasking of the ribosome loading site for methylase synthesis.
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