학술저널
프로리포솜의 제조 및 평가
Preparation and Evaluation of Proliposome
- 대한약학회
- 약학회지
- 제32권 제4호 (1988년)
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1988.08234 - 238 (5 pages)
- 5
Proliposome of Sudan IV was prepared according to Payne et al. and evaluated for it''s size distribution, surface characteristics and conversion to liposome in aqueous medium. The manufacturing procedures for proliposomes involve the coating of phospholipid solution with Sudan IV on the surface of sorbitol particle in rotary vacuum evaporator. As a result, dry, free flowing and stable proliposome was obtained and multi-lamellar liposome of Sudan IV was formed spontaneously when water were added to this. Proliposomes were expected as a probable answer for the physical instability of conventional liposomes.
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