학술저널
혈장내 Pentoxifylline과 Metabolite(I)의 HPLC에 의한 분석
Determination of Pentoxifylline and Metabolite(I) by HPLC
- 대한약학회
- 약학회지
- 제32권 제6호 (1988년)
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1988.12415 - 419 (5 pages)
- 0
A rapid and simple method for the determination of pentoxifylline and its major metabolite, metabolte(I) in plasma was examined by HPLC. For the purification and enrichment of drug from plasma, solid-phase extraction was examined using Sep-pak C18 cartridge. The effectiveness of test method was proved by monitoring of the rat after oral administration of pentoxifylline in a dose of 40mg/kg.
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