대기중 부유분진에 함유된 유기물의 분획별 돌연변이원성

Mutagenicity by Several Fractions of Organic Matter Extracted from Airborne Particulates Collected in atmosphere

The extractable organic matter was extraced from airborne particulates collected in Seoul during 1986. It was fractionated to several fractions and mutagenicities of them were tested in Salmonella thyphimurium TA98 by Ames method. The neutral fraction showed the highest indirect acting mutagenicity while the highest direct acting mutagenicity was observed in the acidic fraction. Indirect acting mutagenicity of airborne particulate was attributed to its neutral fraction about 88% in average, to acidic about 10% in average and to basic fraction about 2% in average. Direct acting mutagenicity of airborne particulate was attributed to its neutral fraction about 70%, to acidic fraction about 29% and to basic fraction about 1%. Among five subtractions of neutral fraction, the proportion of mutagenicity of polynuclear aromatic hydrocarbon subtraction was 13.2% in indirect acting mutagenicity and 5.0% in direct acting mutagenicity.