학술저널
Ditertiary Diamine의 Regiospecific N-, N''-Monoalkyl화 반응
Rigiospecific N-, N''-Monoalkylation of Ditertiary Diamines
- 대한약학회
- 약학회지
- 제34권 제4호 (1990년)
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1990.08244 - 251 (8 pages)
- 0
N-Monoalkylations of ditertiary diamines succeed best in nitromethane or ethanol at low temperature. Unsymmetrical 1,2-diaminoethane, 1,3-diaminopropane and piperazine compounds react selectively under these conditions at the sterically less hindered nitrogen atom.
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