학술저널
항바이러스제 Transdermal Patch의 제조와 평가
Evaluation of Transdermal Patch for Antiviral Agen
- 대한약학회
- 약학회지
- 제34권 제6호 (1990년)
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1990.12429 - 433 (5 pages)
- 22
Transdermal patches and polymer membrane were prepared and evaluated for their ability to antiviral agent in vitro. The membrane perpared with styrene and HEMA by 0.5 and 10% of styrene composition. And the transdermal patches were fabricated with this membrane and silastic silicone sheeting. The antiviral agents used were ACV, BVDU and FEAU. The higher HEMA content membranes exhibited relatively high release rate of each drug. Permeation was enhanced by increasing of drug concentration. The parameters of each drug in diffusion experiment with styrene-HEMA membrane were investigated.
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