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드로페리돌의 용출과 안정성에 미치는 결정형의 영향

Effects of Crystal Modification on Dissolution and Stability of Droperidol

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Five crystal modification of droperidol were prepared by recrystallization. They were characterized by UV spectrophotometer, DSC, and X-ray crystallography. Their dissolution patterns were also investigated. After storage of 2 months at 100% humidity, all polymorphic modifications were transformed.

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