학술저널
페놀베타인 유도체합성 및 항암 활성검토: 프로토베르베린에서 C-환의 화학적 변환
Synthesis of Phenolbetaine Derivatives and Their Anti-cancer Activity: Chemical Transformation of C-ring of Protoberberine
- 대한약학회
- 약학회지
- 제40권 제5호 (1996년)
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1996.10487 - 490 (4 pages)
- 2
The 13-hydroxyberbine(1), derived from berberinephenolbetaine, has been derivatized to furnish a variety of compounds such as 13-oxoberbine(2), 13-thioberbine(3), 13-chloroberbine(4), 13-(2-methylaziridine)berbine(5) and 13-carbolactoneberbine(6). Antitumor activity of these compounds was tested.
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