팔미원의 in vitro 면역조절 작용

In vitro Immunomodulating Effects of PALMIWON

PALMI\ON is composed of 8 oriental herbs which has been known to show some pharmacological effects in kidney, blood vessels and immune systems, and used for the treatment of kidney disease, hypertension, nervous disease and diabetic mellitus in the Orient for a long time. Based on our previous report that PALMI\ON showed different effects on immune cells and 0-cells, the immunoreactivity of ICSA (Islet Cell Surface Antibody) with beta-cell (RINm5F) and the cell proliferation and function of interleukin-1beta damaged beta-cells in the presence of PALMIWON were examined. It was observed that PALMIWON significantly inhibited the immunoreactivity of ICSA with beta-cell, and markedly increased cell proliferation and insulin release of interleukin-1beta damaged beta-cells.