학술저널
7-데아자하이포크산틴과 7-데아자아데닌 유도체의 합성
Synthesis of 7-Deazahypoxanthine and 7-Deazaadenine Derivatives
- 대한약학회
- 약학회지
- 제41권 제2호 (1997년)
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1997.04181 - 186 (6 pages)
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A series of 7-deazahypoxanthine and 7-deazaadenine derivatives[6,7.8.9.10,13] as purine antagonists was prepared. The pyrrolidine-5-one derivatives[4,11] were treated vith (C2H5)3OBF4 to give 3-aryl-5-ethoxy-2H-3,4-dihydropyrrole[5,12], which were converted to 7-aryl-7,8-dihydro-7(9H)-deazahy-poxanthine[6,7,8,9,10] and 7-phenyl-2-methyl-7,8- dihydro-7(9H)-deazaadenine[13].
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