학술저널
산오리나무의 세포독성 성분연구
Studies on the Cytotoxic Constituent of Alnus hirsuta(SPACH) RUPR.
- 대한약학회
- 약학회지
- 제41권 제5호 (1997년)
-
1997.10559 - 564 (6 pages)
- 23
To find out antitumor active principles from natural resources, we have evaluated various extracts from the leaves of Alnus hirsuta (Betulaceae). The ethylacetate extract of this plant was found to show a significant cytotoxicity against several kinds of cultured human solid tumor cell lines (AGS, A5 49, HCT15, SKOV3, HEP3B) in vitro. Using cytotoxicity-guided chromatographic purification of the ethylacetate extract, cytotoxic constituent:1,7-bis-(4-hydroxyphenyl)-5-(beta-D-glucopyranosyloxy)-3-heptanone, was isolated and structurally identified by physico-chemical properties and spectroscopic evidences.
(0)
(0)