학술저널
1N-알킬-2-아미노-3-에톡시카르보닐-피리디노 [2,3-f]인돌-4,9-디온 유도체의 합성 (I)
Synthesis of 1N-alkyl-2-amino-3-ethoxycarbonyl-pyridino [2,3-f]indole-4,9-dione derivatives (I)
- 대한약학회
- 약학회지
- 제41권 제5호 (1997년)
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1997.10575 - 581 (7 pages)
- 2
The 6,7-dichlorquinoline-5,8-dione was reacted with alpha-cyanoacetic acid ethyl ester in ammonia solution to yield 6-(alpha-cyano-alpha-ethoxycarbonyhnethyl)-7-chloroquinoline-5,8-dione (compound I). When this compound was reacted with some alkyl amines (methylamine, ethylamine, isopropylamine, etc) 2-amino-3-ethoxycarbonyl-N-alkyl-pyridino[2,3-f]indole-4,9-diones (compounds II a-e) were obtained.
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