학술저널
쓴맛이 차폐된 편자 고형엘릭실제의 제조 및 평가
Preparation and Evaluation of Coated-Peonja Dry Elixir for Masking the Bitterness
- 대한약학회
- 약학회지
- 제41권 제5호 (1997년)
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1997.10602 - 606 (5 pages)
- 6
Peonjahwan composed of crude herb, and materials and tissue of animals is a considerably bitter and poorly water-soluble oriental medicine for the treatment of hepatitis. Peonja dry elixir and Eudragit-coated peonja dry elixir were prepared using spray-dryer to mask the bitterness and enhance the release of ingredients from peonjahwan. The bitterness of peonja dry elixir and Eudragit-coated peonja dry elixir reduced to 1/2 and 1/4 of that from peonja powder, respectively. Furthermore, the release rate of bound bilirubin from dry elixir was significantly higher than that from peonja powder.
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