학술저널
승마 추출물의 항알레르기 효과
Antiallergic Effect of Cimicifuga heracleifolia Extract
- 대한약학회
- 약학회지
- 제42권 제4호 (1998년)
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1998.08403 - 407 (5 pages)
- 26
Effects of the aqueous extract of Cimicifuga heracleifolia (CHAE) on the allergic reactions were investigated. CHAE inhibited systemic anaphylaxis induced by compound 48/80 in mice dose-dependently. Especially, CHAE inhibited compound 48/80-induced systemic anaphylaxis 100% with a dose of 0.5mg/g body weight. CHAE significantly inhibited serum histamine levels induced by compound 48/80. CHAE inhibited histamine release from the rat peritonea] mast cells activated by compound 48/80 or anti-DNP IgE. Our studies provide evidence that CHAE will be beneficial in the treatment of anaphylias.
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