학술저널
키토산 유도체의 담즙산 흡착 활성
The Bile Acid Absorption Activity of Chitosan Derivatives
- 대한약학회
- 약학회지
- 제42권 제6호 (1998년)
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1998.12572 - 575 (4 pages)
- 6
Chitosan has been known to have hypocholesterolemic and hypolipidemic effects in animal studies. Chitosan also absorbs bile acids in vitro and in vivo, which might result in the hypocholesterolemic action. Trialkyl chitosan derivatives were prepared and tested for bile acid absorption activity in vitro. The derivatives showed enhanced absorption capacities which were comparable to cholestyramine.
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