학술저널
새로운 10-옥소다우노마이시논 유도체의 합성
Syntheses of Novel 1O-Oxodaunomycinone Derivatives
- 대한약학회
- 약학회지
- 제43권 제1호 (1999년)
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1999.0211 - 15 (5 pages)
- 7
A brief route for regiospecific synthesis of novel 10-oxodaunomycinone derivatives (10a, b) is described. Dimethoxy-1-tetralone 4 was converted to acetyl tetralone (5a, b) which was oxidized with oxygen to obtain cis-diol compound (8a, b). The construction of (10a, b) was completed by the condensation of phthaloyl dichloride 9 with cis-diol (8a, b).
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