골담초엽의 플라보노이드

The Flavonoids from Caragana Chamlagu Leaves

The phytochemical studies of the leaves of Caragana chamlagu were carried out as a sieries of the investigation of medicinal resources. The roots of Caragana chamlagu have been used as neuralgia, arthritis and migraine in the folk medicines of Korea. The methanolic extract of the leaves of Caragana chamlagu was suspended with water and then separated with chloroform. Compound I was isolated from precipitates of these water fraction by recrystalization. The aqueous fraction of MeOH extract was performed to column chromatography on Amberhte XAD-4 and Sephadex LH-20, and three compounds, compound II, compound III, and compound IV were isolated. The structures of the four compounds were elucidated by spectroscopic data of 1H-NMR, 13C-NMR, IR, and FAB-MS. Compound I-IV were tilianine (acacetin-7-O-beta-D-glycopyranoside), rutin(quercetin-3-O-alpha-L-rhamnopyranosyl(1->6)-beta-D-glu-copyranoside), kaempferol-3-O-alpha-L-rhamnopyranosyl(l->6)-beta-galactopyranoside, and apigetrin, (apigenin7-O-beta-D-glycopyranoside), respectively.