학술저널
백강잠의 세포독성성분
Cytotoxic Constituents of Bombycis corpus
- 대한약학회
- 약학회지
- 제43권 제2호 (1999년)
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1999.04169 - 172 (4 pages)
- 33
The acivity-guided fractionation on the MeOH extract of Bombycis corpus inoculated by Beauberia bassiana 101A led to the isolation of two steroids, 24-ethylcholest-4-ene-3,6-dione (1) and ergosterol peroxide (2), as active principles. Compounds 1 and 2 exhibited cytotoxicity against cultured human tumor cell fines, A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 with ED50 values ranging from 3.42 to 11.37mcg/ml.
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