학술저널
무우자갈버섯(Hebeloma crustuliniforme) 배양 균사체로부터 분리한 단백다당체 분획 HCA의 항암 및 백혈구감소증 억제효과
Antitumor and Antileukopenic Activity of HCA, the Protein-polysaccharide Fraction of Cultured Mycelia of Hebeloma crustuliniforme
- 대한약학회
- 약학회지
- 제43권 제5호 (1999년)
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1999.10629 - 634 (6 pages)
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A protein-polysaccharide fraction was isolated from the mycelial culture of a Korean basidiomycetous fungus, Hebeloma crustuliniforme, and was named HCA(Hebeloma crustuliniforme fraction A). When intraperitoneally injected at 200mg/kg/day once daily for 10 days, HCA inhibited the growth of sarcoma 180 solid tumor in ICR mice by 65.1%(p<0.05). HCA also exerted protective effect against leukopenia induced by cyclophosphamide with the protection ratio of 39.7%(p<0.01)
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