학술저널
알릴티오필다진 유도체 합성 및 UV-C 조사에 대한 방어효과
Synthesis of Allylthiopyridazine Derivatives and their Protective Effects of UV-C Irradiation
- 대한약학회
- 약학회지
- 제44권 제1호 (2000년)
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2000.029 - 15 (7 pages)
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Four 3-alkoxy-6-allylthiopyridazines and 3-chloro-6-allylthiopyfidazine were synthesized and their protective effects against oxidative stress and UV-C irradiation were tested. 3-Methoxy-6-allylth-iopyridazine and 3-ethoxy-6-allylthiopyridazine did not show protective effect on the oxidative stress but showed the strongest protective effect on UV-C irradiation among the tested compounds. Especially 500mcg/ml of the two compounds was the most effective concentration.
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