황금 Baicalein의 위염 및 H. pylori 균에 미치는 효과

Antigastritic and Anti Helicobacter pylori Effects of Baicalein from Scutellaria Baicalensis

Scutellaria Radix, the dried roots of Scutellaria baicalensis Georgi (Labiatae). has been used in oriental traditional medicine for treatment of fever, urine disorder, diarrhea, inflammation. Present study was carried out for the gastroprotective effect of chrysin, baicalcin, baicalin, wogonin wogonin from Scutellaria baicalensis. This reports evaluated antioxidant effect, antibacterial activity against Helicobacter pylori and HCl·ethanol-induced gastric lesion in rats and showed the significant effectiveness. It may be regarded that the antigastritic effects and antibacterial activity of baicalin, baicalein from scutellaria baicalensis are originated from acid-neutralizing capacity, free radical scavenging effects and the antibacterial activity against Helicobacter pylori.