유레아 및 티오유레아 유도체의 합성과 활성화된 대식세포의 NO 생성 저해효과
Synthesis of Urea and Thiourea Derivatives and Their Inhibitory Activities of NO Production by Activated Macrophages

대한약학회
약학회지
제51권 제4호 (2007년)
2007.08

246 - 252 (7 pages)

Several ureas and thioureas were designed and synthesized and their inhibitory activities of NO production in lipopolysaccharide-activated macrophages were evaluated. Among these compounds, indole-containing thiourea 6e was the most potent showing 17.4 μM of IC50 value.

유레아 및 티오유레아 유도체의 합성과 활성화된 대식세포의 NO 생성 저해효과
Synthesis of Urea and Thiourea Derivatives and Their Inhibitory Activities of NO Production by Activated Macrophages

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유레아 및 티오유레아 유도체의 합성과 활성화된 대식세포의 NO 생성 저해효과 Synthesis of Urea and Thiourea Derivatives and Their Inhibitory Activities of NO Production by Activated Macrophages

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유레아 및 티오유레아 유도체의 합성과 활성화된 대식세포의 NO 생성 저해효과
Synthesis of Urea and Thiourea Derivatives and Their Inhibitory Activities of NO Production by Activated Macrophages

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