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물오리나무에서 분리된 Diarylheptanoid의 항산화작용

Antioxidative Effects of Diarylheptanoids from Alnus hirsuta

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Four diarylheptanoids oregonin, hirsutanonol, 1,7-bis-(3,4-dihydroxyphenyl)-heptane-5-0-beta-D-xylopyranoside and 1,7-bis-(3,4-dihydroxyphenyl)-heptane-5-0-beta-D-glucopyranoside isolated from Alnus hirsuta were evaluated for their antioxidative effects with 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and lipid peroxidation generation system mediated by addition of H202 and/or Fe2+, to rat liver homogenate. All these diarylheptanoids showed significant inhibitory activities against the DPPH radical and demonstrated strong activities in preventing the lipid peroxidation induced by H202.

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