9,10-디플루오르-5,6,6a,7,11b-펜타하이드로인다노[2,1-c]이소퀴놀린의 합성
Synthesis of 9,10-difluoro-5,6,6a,7,11b-pentahydroindano [2,1-c]isoquinoline

대한약학회
약학회지
제44권 제6호 (2000년)
2000.12

505 - 510 (6 pages)

The synthesis of pentahydroindanoisoquinoline (4) compound has been achieved via the cyclization of 2-(N-benzylamino)-5,6-difluoro-1-indanol (10a, 10b), which was prepared by condensation and reduction of 2-amino-1-indanol and benzaldehyde in ethanol. The stereochemistry of H6a and H11b of 9,10-difluoro-5,6,6a,7,11b-pentahydroindano[2,1-c]isoquinoline (4) was the trans B/C ring fusion.

9,10-디플루오르-5,6,6a,7,11b-펜타하이드로인다노[2,1-c]이소퀴놀린의 합성
Synthesis of 9,10-difluoro-5,6,6a,7,11b-pentahydroindano [2,1-c]isoquinoline

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9,10-디플루오르-5,6,6a,7,11b-펜타하이드로인다노[2,1-c]이소퀴놀린의 합성 Synthesis of 9,10-difluoro-5,6,6a,7,11b-pentahydroindano [2,1-c]isoquinoline

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9,10-디플루오르-5,6,6a,7,11b-펜타하이드로인다노[2,1-c]이소퀴놀린의 합성
Synthesis of 9,10-difluoro-5,6,6a,7,11b-pentahydroindano [2,1-c]isoquinoline

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