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Bis(pyronyl)acrylic Acid Ester 유도체의 합성

Synthesis of Bis(pyronyl)acrylic Acid Ester Derivatives

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Dicaffeoyltartaric acid has a structural feature consisting of two caffeic acid units separated by tartaric acid linker and has been found to be a potent inhibitor of HIV-1 integrase and an antioxidant. In this study, bis(pyronyl)acrylic acid esters joined through a 5-membered ring as a linker were synthesized as the analogues of dicaffeoyltartaric acid.

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