학술저널
오매(Mume Fructus) 추출물의 혈행개선 효과
The Effects of Mume Fructus Extracts on Blood Flow Improvement
- 대한약학회
- 약학회지
- 제53권 제5호 (2009년)
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2009.10298 - 302 (5 pages)
- 164
Mume Fructus extract is used in folk medicine in Eastern Asian countries including Korea. However, its therapeutic effect on thrombosis is not known. Mume Fructus methanol extract (ME) dose-dependently inhibited ADP-induced platelet aggregation and also exhibited about 130% fibrinolytic activity compared to the natto. Oral administration of ME to mice significantly extended tail-bleeding time. ME prolonged both aPTT and PT in human citrated plasma also. These results suggest that the methanol extract from Mume Fructus have antithrombosis activity.
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