학술저널
인삼 사포닌과 다당류 혼합물의 활성화된 RAW264.7 세포주에 대한 염증조절 효과
The Inflammation-modulatory Effects of Ginseng Saponin and Polysaccharide on Activated RAW264.7 Cell-line
- 대한약학회
- 약학회지
- 제54권 제2호 (2010년)
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2010.04134 - 141 (8 pages)
- 43
It is well known that the numbers and functions of immune-associated cells are increased by saponins and polysaccharides in ginseng. In this study, the mixture of polysaccharide and saponin (MPS) from Panax ginseng is applied to LPS- activated RAW 264.7 cells. The production of NO and the gene expression of IL-6 and TNF-α are decreased in LPS-activated RAW 264.7 cells and the expression of arginase II and PD-1L genes is decreased in LPS-untreated macrophages. Therefore, the mixture of saponin and polysaccharide from Panax ginseng could be used in order to regulate immune responses.
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