펨토초 레이저와 미세각막절삭기를 이용한 라식에서 각막내피세포의 변화 비교

Comparision of Corneal Endothelial Change in Femtosecond Laser and Microkeratome LASIK

Purpose: To compare the corneal endothelial cell change in Femtosecond laser and microkeratome LASIK operation. Methods: This study involved 31 eyes (16 patients) that had LASIK using a femtosecond laser (group 1). The control group comprised 32 eyes (16 patients) that had conventional LASIK using microkeratome. We measured the endothelial cell using a non-contact specular microscope preoperatively and at postoperative 1, 2 and 6 months. Results: The preoperative and postoperateive 1, 2, and 6 months cell densities were, respectively: (group 1) 3039±335.2, 3012.9±373.0, 3008.2±240.2, 3009.1±250.5; (group 2) 2984.8±334.4, 2972.7±290.0, 2968±323.2, 2968±319.1. The coefficients of variation were, respectively: (group 1) 32.6±5.3, 33±7.2, 32.2±5.9, 31.7±5.8; (group 2) 32.3±5.3, 33.6±6.2, 35.5±4.8, 34.1±5.1. Respective hexagonality measurements were: (group 1) 59.2±11.7, 56±12.1 55.1±13.5, 57.2±11.6; (group 2) 57.6±9.8, 57.4±10.7, 56.5±11.6, 57.1±11.1. Conclusions: There was no statistical difference in corneal endothelial change between the two groups (p>0.05). LASIK using the femtosecond laser seemed to be a safe choice when considering corneal endothelial change.