당뇨황반부종에서 황반부 망막두께의 하루변화

Diurnal Variation of Macular Thickness in Diabetic Macular Edema

Purpose: To evaluate the diurnal variation of macular thickness in eyes with diabetic macular edema. Methods: We measured macular thickness using optical coherence tomography in 33 eyes with diabetic macular edema and 33 normal control eyes at 7 am, 11am, 2pm, and 5 pm. We investigated the correlation between macular thickness change and several factors such as sex, duration of diabetes mellitus, presence of hypertension, HbA1c, creatinine clearance, blood urea nitrogen, serum creatinine, blood sugar, blood pressure, severity of diabetic retinopathy, and whether PRP was done or not. Results: Retinal thickness in 3.45 mm macular area was the thickest at 7 am and then decreased over the day to be thinnest at 5 pm (p≤0.01). There was a significant correlation between macular thickness and macular thickness change (p≤0.01). However, there was no relationship between other factors and macular thickness change. Conclusions: Retinal thickness in diabetic macular edema decreased over the day and macular thickness change tended to increase according to macular thickness.