설페라존을 사용하여 치료한 크렙시엘라 뉴모니아 내인성 안내염 2예

Two Cases of Klebsiella Pneumoniae Endogenous Endophthalmitis Treated with Sulperazone

Purpose: To report and review 2 cases of Klebsiella Pneumoniae endogenous endophthalmitis showing multi drug resistance that were treated with sulperazone. Methods: Sulperazone was administered to two patients with Klebsiella Pneumoniae endogenous endophthalmitis: a 51-year-old male with orbital cellulitis who showed no response to vancomycin, ceftazidime, and amikacin for 6days; and a 67-year-old female who showed no response to cefotaxime, and amikacin. Results: Proptosis and inflammation began to improve after changing to sulperazone. Therefore, enucleation and debridement could be avoided. Conclusions: Good results were obtained by use of Sulperazone which inactivates beta-lactamase irreversibly and which showed bactericidal effect to multi drug resistant Klebsiella Pneumoniae endogenous endophthalmitis.