원발성 항인지질증후군에서 발생한 양안의 망막중심정맥폐쇄

Bilateral Central Retinal Vein Occlusion in Primary Antiphospholipid Syndrome

Purpose: To Report a case of bilateral central retinal vein occlusion (CRVO) caused by primary antiphospholipid syndrome. Methods: A 38-year-old male is referred to the department of ophthalmology for the bilateral visual loss. Results: On initial visit, both visual acuity was 0.3. Upon consider changing to fundoscopic examination, the patient was diagnosed with bilateral CRVO. We performed hematologic tests including thrombophilia examination. There were no abnormal findings on routine hematologic tests. Antinuclear antibody and rheumatoid factor were negative but anticardiolipin antibodies presented high titer, on two occasions six weeks apart. We prescribed oral aspirin and performed intravitreal bevacizumab injection under the diagnosis of bilateral CRVO in primary antiphospholipid syndrome. Conclusions: It may be necessary to check antiphospolipid antibody in cases of bilateral CRVO in young patients without medical problem. J Korean Ophthalmol Soc 48(10):1433-1437, 2007