원발개방각녹내장에서 중심각막두께와 시야손상의 관계

Central Corneal Thickness and Visual Field Progression in Primary Open-Angle Glaucoma

Purpose: To find difference in the rate of visual field defect progression among primary open angle glaucoma (POAG) patients grouped according to central corneal thickness (CCT). Methods: The medical records of 87 eyes of 87 POAG patients who received were on regular treatment and had a minimum of 5 years of longitudinal Humphrey automated visual field follow-up were reviewed retrospectively. The patients were divided into 4 quartile groups by CCT, and the correlations among clinical factors, such as intraocular pressure (IOP), and change in mean deviation (MD), were analyzed. Results: The thinner cornea group showed a significant trend foward higher average, maximal, and yearly maximal IOP when the IOP was corrected by CCT (p<0.01), The rate of change in MD is significantly different; -0.33±0.6dB, -0.28±0.4dB, -0.09±0.2dB ,-0.02±0.2dB starting with the thinnest cornea group (p=0.036). Correlation analysis revealed a significant correlation between CCT and the rate of change in MD (r=0.351, p=0.001). Conclusions: In POAG patients who were on regular treatment at a tertiary referral hospital, patients with thinner cornea showed faster visual field defect progression.