213-nm Solid-State Laser 굴절교정각막절제술 시 각막표면 수분의 영향

Influence of Surface Fluid during Photorefractive Keratectomy Using a 213-nm Solid-State Laser

Purpose: To investigate the effect of surface fluid on the ablation rate and efficacy of 213-nm solid-state laser during photorefractive keratectomy (PRK). Methods: Twelve rabbits (24 eyes) underwent myopic PRK for the correction of 10 diopters using 213-nm solid-state laser. Photoablation was performed with removal of corneal surface fluid using the Weckcel&reg; sponge every 5 seconds in one eye and without removal of corneal surface fluid in the control eye. The mean central corneal thickness (CCT) was evaluated preoperatively, and at 1 week, 4 weeks postoperatively. Results: The mean CCT of group 1 (with removal of corneal surface fluid) were 361.3±13.9 μm preoperatively and 321.4±18.5 μm at 4 weeks postoperatively. The mean CCT of group 2 (without removal of surface fluid) were 358.7±8.9 μm preoperatively and 338.4±12.0 μm at 4 weeks postoperatively. The mean ablation depths were 39.8±7.4 μm in group 1 and 20.3±5.8 μm in group 2 at 4 weeks postoperatively (p<0.05). Conclusions: Induced corneal surface fluid during PRK may influence the ablation efficacy and accuracy of solid-state laser. This result should be considered in clinical trialswith 213-nm solid-state laser, especially in high myopes. J Korean Ophthalmol Soc 2008;49(11):1723-1728