망막분지정맥폐쇄에서 시행한 조직플라스미노겐활성체 및 C3F8의 유리체강내주입술

Intravitreal Tissue Plasminogen Activator with C3F8 Injection in Branch Retinal Vein Occlusion

`Purpose: To evaluate the efficacy of intravitreal tissue plasminogen activator (tPA) with C3F8 injection for branch retinal vein occlusion (BRVO) involving fovea. Methods: Seven patients (7 eyes) presenting with subfoveal hemorrhage caused by BRVO were treated with an intravitreal tPA and C3F8 injection. We assessed the visual acuity (VA) and foveal thickness measured with optical coherence tomography. Results: The mean duration of symptoms before surgery was 5.42±1.90 weeks. The mean logMAR VA improved from 1.14±0.19 at baseline to 0.87±0.34 at one week and 0.30±0.32 at six months. The mean foveal thickness decreased from 564.421±186.88 ?m at baseline to 483.14±275.06 μm at one week and 353.28±152.99 μm at six months. There was no adverse effect related to the treatment. Conclusions: Intravitreal tPA with C3F8 injection may be an effective treatment for resolving macular edema with subfoveal hemorrhage and improving the VA in recently developed BRVO. `