당뇨황반부종에서 다국소 망막전위도검사와 치료 후 시력과의 상관관계

Correlation Between Multifocal Electroretinography and Visual Acuity After Resolution of Diabetic Macular Edema

Purpose: To evaluate the prognostic value of multifocal electroretinography (mfERG) after a decrease of retinal thickness in eyes with diabetic macular edema (DME). Methods: Sixty patients (60 eyes) underwent intravitreal injection of triamcinolone acetonide or bevacizumab for diabetic macular edema. Eyes were divided into three groups, according to foveal thickness : Group A (<500 μm, n=20 eyes), Group B (500 μm&#8806; <800 μm, n=20 eyes), and Group C (&#8807;800 μm, n=20 eyes). Best-corrected visual acuity (BCVA) and mfERG responses from the most central seven hexagons were analyzed both before and after treatment. Results: The pre-injection P1 amplitudes of mfERG correlated significantly with end-point BCVA in Groups A and B (p<0.05), but did not correlate with end-point BCVA (p>0.05) in Group C. Conclusions: The level of P1 amplitudes of mfERG may be a useful tool to predict visual outcomes after a decrease of retinal thickness in patients with diabetic macular edema. J Korean Ophthalmol Soc 2010;51(1):29-34