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A Case of an Orbital Myxoma

Purpose: Orbital myxoma is an extremely rare tumor. To date, only a few cases have been reported in the literature. The present study reports a case of an orbital myxoma and demonstrates the clinical and histological features. Case summary: A 37-year-old woman presented with a painless movable mass in the orbital margin of the left eye. Computed tomography of the orbit revealed a sharply outlined solid mass, and an excisional biopsy was performed. The excised specimen consisted of a 17x9x10 mm3 brownish mass of scattered spindle cells and small vascular spaces in a fibromyxoid background. Immunohistochemically, the tumor cells were not immunoreactive for SMA, S-100 protein or CD34. Histopathologic examination revealed the tumor to be a myxoma. There was no mass lesion in computed tomography of the orbit, and no recurrence or complications were found one month after removal. Conclusions: When a patient presents with a painless and movable mass in the orbital area, orbital myxoma should be considered as a possible diagnosis. The orbital myxoma with bone invasion should be completely removed to prevent the lesion from recurring. J Korean Ophthalmol Soc 2010;51(8):1142-1145