양안 결막 아밀로이드증 진단과 결막종괴절제 및 냉동치료술 1예

A Case of Bilateral Conjunctival Amyloidosis Treated with Mass Excision and Cryotherapy

Purpose: To report the treatment results of mass excision and cryotherapy in a case of bilateral conjunctival amyloidosis. Case summary: A 72-year-old man with conjunctival mass and foreign body sensations in both eyes visited our clinic. He was previously diagnosed with conjunctival lymphoma after conjunctival biopsy at another hospital. A yellow-pink colored mass was observed in the bulbar conjunctiva. A repeated conjunctival biopsy revealed the mass to be amyloid, consistent with the cervical lymph node biopsy results, and the diagnosis was changed to primary systemic amyloidosis. The patient was treated with melphalan and prednisolone; however, the ocular pain, symblepharon, and conjunctival mass progressed. A 360 degree conjunctivoperiotomy, mass excision, and repeated cryotherapy were performed in the more severely affected left eye. The patient was followed for one year, and there were no complications or progression of the conjunctival lesion. Conclusions: Conjunctival amyloidosis requires local pathologic confirmation as well as a systemic work-up. If surgical removal is necessary despite systemic treatment, mass excision and cryotherapy may be effective. J Korean Ophthalmol Soc 2011;52(5):628-632