황반원공 수술 후 중심와 주변 미세구조 변화의 장기 결과

Long-Term Changes in Foveal Microstructure after Macular Hole Surgery

Purpose: To evaluate long-term outcome of foveal tissue elongation after macular hole (MH) surgery. Methods: This retrospective, observational case series was performed on patients who underwent MH surgery and were followed-up more than 12 months. Distance between the parafoveal edge of the outer plexiform layer (OPL) was defined as the inter-OPL distance and measured using optical coherence tomography images at 5 to 8 months postoperatively and at the last follow-up. The horizontal and vertical inter-OPL distances were compared between the 2 defined time points. In addition, further elongation of the foveal tissue in certain directions was defined as asymmetric elongation and was compared between the defined time points. Results: The early and late postoperative examination was performed at 6.3 ± 1.1 (mean ± standard deviation) months and 22.7 ± 7.8 months, respectively. The horizontal inter-OPL distance was 552.3 ± 130.5 μm and 502.8 ± 139.3 μm at the defined time points, respectively and the vertical inter-OPL distance was 478.9 ± 107.2 μm and 447.5 ± 107.1 μm, respectively. Both horizontal and vertical inter-OPL distances were significantly shortened at the last postoperative examination (p < 0.001, p = 0.002, respectively). The degree of asymmetric elongation was 10.8 ± 6.5% and 11.8 ± 7.9% at the defined time points, respectively, and was not different between the defined time points (p = 0.426). Conclusions: The long-term shortening of foveal tissue after MH surgery without progression of asymmetry may partially contribute to the long-term recovery of visual function after MH surgery. J Korean Ophthalmol Soc 2013;54(11):1731-1736